ABSTRACT
Objective To investigate the effect of preoperative percutaneous dilatational trache-otomy (PDT)in oral and maxillofacial surgery anesthesia versus traditional surgical tracheotomy (ST).Methods General data,vital signs,operation time,anesthetics,the amount of bleeding and complications during the procedure were analyzed after reviewing the clinical data of 124 cases under-going radical correction of oral and maxillofacial tumor plus flap transferring and repairing and trache-otomy during May 2013 to May 201 5.Results A total of 124 cases were divided into two groups:PDT group (group P,n =41)and ST group (group S,n =83).There was no significant difference of general data between the two groups.The incision length and operation time were significantly shorter and the amount of bleeding was remarkably lower in group P than those in group S (P <0.05),while the incidence of complications was not significantly different between the two groups.Conclusion PDT has more advantages over traditional ST and is a better airway approach in oral and maxillofacial surgery.
ABSTRACT
The function of spontaneous T suppressor cell (STs) of peripheral blood was detected in 17 patients with acute schistosomiasis japonica, 14 cases with chronic schistosomiasis and 25 patients with advanced schistosomiasis. The subset of T cell were simultaneously phenotyped in all cases except 10 patients with advanced schistosomiasis. Among the patients with acute schistosomiasis the rates of OKT3 + (pan T cell), OKT4+ (helper T cell) and OKT8 + (suppressor/cytotoxic T cell) were all significantly increased, and the function of STs was normal. In chronic and advanced schistosomiasis, the rate of OKT8 + T cell was raised, the rate of OKT3+ T cell and ratio of OKT4+/OKT8+ were statistically reduced, and the function of STs was significantly increased. The rate of OKT8+ T cell was negatively correlated with the function of STs in acute schistosomiasis, whereas in chronic and advanced rchistosomiasis, the rate of OKT8 + T cell had significant positive correlation with STs function while OKT4 +/OKT8 + had significant negative correlation with this function. The results indicate that the cellular immune response is increased in patients with acute schistosomiasis and down regulated in patients with chronic and advanced schistosomiasis. The function of T suppressor cell and the subset of T cell may play an important role in the immunoregulation of patients with schistosomiasis japonica.
ABSTRACT
Activity of IL-1 produced by peripheral blood monocytes stimulated with lipopolysaccharide in vitro was detected from 17 acute cases, 14 chronic cases and 19 advanced cases of schistosomiasis japonica. It was found that the level of IL-1 was significantly increased and positively related to the body tempereture in the group with acute schistosomiasis. The activity of IL-1 was statistically reduced in the chronic and advanced groups, especially in the latter. After inhibiting the synthesis of prostaglandin with indomethacin, the level of IL-1 was significantly increased in three groups of patients, but no apparent change in the normal contro group. The results indicate that IL-1 may play an important role in inducing the inflammatory reaction in patients with acute schistosomiasis japonica and in the immunoregulation in the chronic stage. The changes of IL-1 activity in patients with schistosomiasis japonica may be closely related to prostaglandin.